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In Vivo Methods to Study Uptake of Nanoparticles into the Brain

Several in vivo techniques have been developed to study and measure the uptake of CNS compounds into the brain. With these techniques, various parameters can be determined after drug administration, including the blood-to-brain influx constant (K(in)), the permeability-surface area (PS) product, and...

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Main Authors: van Rooy, Inge, Cakir-Tascioglu, Serpil, Hennink, Wim E., Storm, Gert, Schiffelers, Raymond M., Mastrobattista, Enrico
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044085/
https://ncbi.nlm.nih.gov/pubmed/20924653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0291-7
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