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In Vivo Methods to Study Uptake of Nanoparticles into the Brain

Several in vivo techniques have been developed to study and measure the uptake of CNS compounds into the brain. With these techniques, various parameters can be determined after drug administration, including the blood-to-brain influx constant (K(in)), the permeability-surface area (PS) product, and...

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Bibliografiske detaljer
Main Authors: van Rooy, Inge, Cakir-Tascioglu, Serpil, Hennink, Wim E., Storm, Gert, Schiffelers, Raymond M., Mastrobattista, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044085/
https://ncbi.nlm.nih.gov/pubmed/20924653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0291-7
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