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Transformation of normal rat kidney (NRK) cells by an infectious retrovirus carrying a synthetic rat type alpha transforming growth factor gene.

We synthesized a gene for rat type alpha transforming growth factor (TGF-alpha) consisting of the leader sequence and the sequence coding for the mature 50-amino acid peptide without the C-terminal processed region. This gene was inserted into the retrovirus vector pSW272, which is derived from sple...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Watanabe, S, Lazar, E, Sporn, M B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1258
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