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Gene transfer, expression, and sarcomeric incorporation of a headless myosin molecule in cardiac myocytes: evidence for a reserve in myofilament motor function

The purpose of this study was to implement a living myocyte in vitro model system to test whether a motor domain-deleted headless myosin construct could be incorporated into the sarcomere and affect contractility. To this end we used gene transfer to express a “headless” myosin heavy chain (headless...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vandenboom, Rene, Herron, Todd, Favre, Elizabeth, Albayya, Faris P., Metzger, Joseph M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044057/
https://ncbi.nlm.nih.gov/pubmed/21112946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00786.2009
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