Detrimental effects of thyroid hormone analog DITPA in the mouse heart: increased mortality with in vivo acute myocardial ischemia-reperfusion

There is emerging evidence that treatment with thyroid hormone (TH) can improve postischemic cardiac function. 3,5-Diiodothyropropionic acid (DITPA), a TH analog, has been proposed to be a safer therapeutic agent than TH because of its negligible effects on cardiac metabolism and heart rate. However...

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Detalhes bibliográficos
Main Authors: Hassan Talukder, M. A., Yang, Fuchun, Nishijima, Yoshinori, Chen, Chun-An, Xie, Lin, Mahamud, Shouvik D., Kalyanasundaram, Anuradha, Bonagura, John D., Periasamy, Muthu, Zweier, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044051/
https://ncbi.nlm.nih.gov/pubmed/21131480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00514.2010
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