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Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation

The differentiation of valvular interstitial cells (VICs) to a myofibroblastic or osteoblast-like phenotype is commonly found in calcific valvular stenosis, although the molecular-level mechanisms of this process remain poorly understood. Due to the role of the Rho pathway in various vascular diseas...

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Autori principali: Gu, Xiaoxiao, Masters, Kristyn S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044049/
https://ncbi.nlm.nih.gov/pubmed/21131478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01178.2009
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