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Efficacy of simvastatin treatment of valvular interstitial cells varies with the extracellular environment

OBJECTIVE: The lack of therapies that inhibit valvular calcification and the conflicting outcomes of clinical studies regarding the impact of 3-hydroxy-3-methylglutaryl-coenzyme A (HMGCoA) reductase inhibitors on valve disease highlight the need for controlled investigations to characterize the inte...

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Autori principali: Monzack, Elyssa L., Gu, Xiaoxiao, Masters, Kristyn S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701301/
https://ncbi.nlm.nih.gov/pubmed/19023089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.179218
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