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Tissue Factor and Tissue Factor Pathway Inhibitor as Key Regulators of Global Hemostasis: Measurement of Their Levels in Coagulation Assays

The tissue factor (TF)/factor (F)VIIa complex is the primary initiator of coagulation in vivo. Tissue factor pathway inhibitor (TFPI) is the physiological inhibitor of the TF/FVIIa complex. Deficiencies of either TF or TFPI have not been reported in humans, and a complete absence of either of these...

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Detalhes bibliográficos
Main Authors: Kasthuri, Raj S., Glover, Sam L., Boles, Jeremiah, Mackman, Nigel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043987/
https://ncbi.nlm.nih.gov/pubmed/20978997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0030-1265293
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