Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown

There is increasing evidence that the neutrophil chemoattractant proline-glycine-proline (PGP), derived from the breakdown of the extracellular matrix, plays an important role in neutrophil recruitment to the lung. PGP formation is a multistep process involving neutrophils, metalloproteinases (MMPs)...

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Main Authors: Braber, Saskia, Koelink, Pim J., Henricks, Paul A. J., Jackson, Patricia L., Nijkamp, Frans P., Garssen, Johan, Kraneveld, Aletta D., Blalock, J. Edwin, Folkerts, Gert
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043817/
https://ncbi.nlm.nih.gov/pubmed/21112944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00304.2010
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