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TNF/TNFR1 signaling mediates doxorubicin-induced diaphragm weakness
Doxorubicin, a common chemotherapeutic agent, causes respiratory muscle weakness in both patients and rodents. Tumor necrosis factor-α (TNF), a proinflammatory cytokine that depresses diaphragm force, is elevated following doxorubicin chemotherapy. TNF-induced diaphragm weakness is mediated through...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043812/ https://ncbi.nlm.nih.gov/pubmed/21097524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00264.2010 |
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