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Distinct DNA methylation changes highly correlated with chronological age in the human brain
Methylation at CpG sites is a critical epigenetic modification in mammals. Altered DNA methylation has been suggested to be a central mechanism in development, some disease processes and cellular senescence. Quantifying the extent and identity of epigenetic changes in the aging process is therefore...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043665/ https://ncbi.nlm.nih.gov/pubmed/21216877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq561 |
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