Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues. We present a set of integrated experiments that investigate the effects of common genetic variability on DNA methylation and mRNA expr...

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Detalhes bibliográficos
Main Authors: Gibbs, J. Raphael, van der Brug, Marcel P., Hernandez, Dena G., Traynor, Bryan J., Nalls, Michael A., Lai, Shiao-Lin, Arepalli, Sampath, Dillman, Allissa, Rafferty, Ian P., Troncoso, Juan, Johnson, Robert, Zielke, H. Ronald, Ferrucci, Luigi, Longo, Dan L., Cookson, Mark R., Singleton, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869317/
https://ncbi.nlm.nih.gov/pubmed/20485568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000952
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