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Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells

Epithelial proliferation, critical for homeostasis, healing, and colon cancer progression, is in part controlled by epidermal growth factor receptor (EGFR). Proliferation of colonic epithelia can be induced by Citrobacter rodentium infection, and we have demonstrated that activity of tumor suppresso...

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Detalhes bibliográficos
Main Authors: Qi, Wentao, Weber, Christopher R., Wasland, Kaarin, Roy, Hemant, Wali, Ramesh, Joshi, Suhasini, Savkovic, Suzana D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043652/
https://ncbi.nlm.nih.gov/pubmed/21109589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00416.2010
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