Hypothermic Circulatory Arrest Increases Permeability of the Blood Brain Barrier in Watershed Areas

BACKGROUND: Integrity of the blood brain barrier (BBB) after cardiopulmonary bypass (CPB) with hypothermic circulatory arrest (HCA) is controversial in children. We tested the hypothesis that BBB is disrupted by HCA. METHODS: 41 piglets (mean weight 11 kg) were randomly divided into acute and surviv...

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Main Authors: Okamura, Toru, Ishibashi, Nobuyuki, Kumar, T Susheel, Zurakowski, David, Iwata, Yusuke, Lidov, Hart G. W., Jonas, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043641/
https://ncbi.nlm.nih.gov/pubmed/21095352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2010.06.118
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