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Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice

Adipose tissue inflammation and reduced pancreatic β-cell function are key issues in the development of cardiovascular disease and progressive metabolic dysfunction in type 2 diabetes mellitus. The aim of this study was to determine the effect of the DPP IV inhibitor sitagliptin on adipose tissue an...

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Autori principali: Dobrian, A. D., Ma, Q., Lindsay, J. W., Leone, K. A., Ma, K., Coben, J., Galkina, E. V., Nadler, J. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043624/
https://ncbi.nlm.nih.gov/pubmed/21081706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00463.2010
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