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Back to the future: covalent epitope-based HIV vaccine development

Traditional HIV vaccine approaches have proved ineffective because the immunodominant viral epitopes are mutable and the conserved epitopes necessary for infection are not sufficiently immunogenic. The CD4 binding site expressed by the HIV envelope protein of glycoprotein 120 is essential for viral...

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Detalhes bibliográficos
Main Authors: Paul, Sudhir, Planque, Stephanie, Nishiyama, Yasuhiro, Escobar, Miguel, Hanson, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043596/
https://ncbi.nlm.nih.gov/pubmed/20822346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erv.10.77
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