Distinct requirements for achievement of allotolerance versus reversal of autoimmunity via non-myeloablative mixed chimerism induction in NOD mice(1)

OBJECTIVES: Mixed hematopoietic chimerism is associated with islet allograft tolerance and may reverse autoimmunity. We developed low intensity regimens for the induction of mixed chimerism and examined effects on autoimmunity in pre-diabetic NOD mice. RESEARCH DESIGN AND METHODS: NOD mice received...

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Hlavní autoři: Nikolic, Boris, Onoe, Takashi, Takeuchi, Yasuo, Khalpey, Zain, Primo, Valeria, Leykin, Igor, Smith, R. Neal, Sykes, Megan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043373/
https://ncbi.nlm.nih.gov/pubmed/20061915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181c4692e
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