Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family.

A direct method for the determination of N-linked glycosylation sites in highly glycosylated proteins is described. Carcinoembryonic antigen (CEA) and a nonspecific crossreacting antigen (NCA) were chemically deglycosylated, and peptide maps were prepared by reverse-phase HPLC. The peptides were seq...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Paxton, R J, Mooser, G, Pande, H, Lee, T D, Shively, J E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.920
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