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Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family.

A direct method for the determination of N-linked glycosylation sites in highly glycosylated proteins is described. Carcinoembryonic antigen (CEA) and a nonspecific crossreacting antigen (NCA) were chemically deglycosylated, and peptide maps were prepared by reverse-phase HPLC. The peptides were seq...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Paxton, R J, Mooser, G, Pande, H, Lee, T D, Shively, J E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.920
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