Uncoordinated Transcription and Compromised Muscle Function in the Lmna-Null Mouse Model of Emery-Dreifuss Muscular Dystrophy

LMNA encodes both lamin A and C: major components of the nuclear lamina. Mutations in LMNA underlie a range of tissue-specific degenerative diseases, including those that affect skeletal muscle, such as autosomal-Emery-Dreifuss muscular dystrophy (A-EDMD) and limb girdle muscular dystrophy 1B. Here,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gnocchi, Viola F., Scharner, Juergen, Huang, Zhe, Brady, Ken, Lee, Jaclyn S., White, Robert B., Morgan, Jennifer E., Sun, Yin-Biao, Ellis, Juliet A., Zammit, Peter S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043058/
https://ncbi.nlm.nih.gov/pubmed/21364987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016651
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge