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Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions

BACKGROUND: PH domains represent one of the most common domains in the human proteome. These domains are recognized as important mediators of protein-phosphoinositide and protein-protein interactions. Phosphoinositides are lipid components of the membrane that function as signaling molecules by targ...

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Detalhes bibliográficos
Main Authors: Jackson, Sean G, Al-Saigh, Sarra, Schultz, Carsten, Junop, Murray S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042905/
https://ncbi.nlm.nih.gov/pubmed/21310079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-11
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