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Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions
BACKGROUND: PH domains represent one of the most common domains in the human proteome. These domains are recognized as important mediators of protein-phosphoinositide and protein-protein interactions. Phosphoinositides are lipid components of the membrane that function as signaling molecules by targ...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042905/ https://ncbi.nlm.nih.gov/pubmed/21310079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-11 |
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