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IL-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells

Infection with HIV-1 induces a progressive deterioration of the immune system that ultimately leads to AIDS. Mouse models indicate that the common gamma chain (γ(c))- sharing cytokine interleukin (IL)-21 and its receptor (IL-21R) play a crucial role in maintaining polyfunctional T cell responses dur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Parmigiani, Anita, Pallin, Maria F., Schmidtmayerova, Helena, Lichtenheld, Mathias G., Pahwa, Savita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042849/
https://ncbi.nlm.nih.gov/pubmed/20977918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2010.10.015
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