A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

Carotenoids are the precursors for vitamin A and are proposed to prevent oxidative damage to cells. Mammalian genomes encode a family of structurally related nonheme iron oxygenases that modify double bonds of these compounds by oxidative cleavage and cis-to-trans isomerization. The roles of the fam...

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Autors principals: Amengual, Jaume, Lobo, Glenn P., Golczak, Marcin, Li, Hua Nan M., Klimova, Tatyana, Hoppel, Charles L., Wyss, Adrian, Palczewski, Krzysztof, von Lintig, Johannes
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2011
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042841/
https://ncbi.nlm.nih.gov/pubmed/21106934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-173906
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