Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism

Mammalian genomes encode two provitamin A-converting enzymes as follows: the β-carotene-15,15′-oxygenase (BCO1) and the β-carotene-9′,10′-oxygenase (BCO2). Symmetric cleavage by BCO1 yields retinoids (β-15′-apocarotenoids, C(20)), whereas eccentric cleavage by BCO2 produces long-chain (>C(20)) ap...

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Detalhes bibliográficos
Main Authors: Amengual, Jaume, Widjaja-Adhi, M. Airanthi K., Rodriguez-Santiago, Susana, Hessel, Susanne, Golczak, Marcin, Palczewski, Krzysztof, von Lintig, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837149/
https://ncbi.nlm.nih.gov/pubmed/24106281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.501049
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