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cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC).

Administration of ethanol to rabbits is known to induce a unique liver microsomal cytochrome P-450, termed isozyme 3a or P-450ALC, which is responsible for the increased oxidation of ethanol and other alcohols and the activation of toxic or carcinogenic compounds such as acetaminophen and N-nitrosod...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Khani, S C, Zaphiropoulos, P G, Fujita, V S, Porter, T D, Koop, D R, Coon, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3027695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.3.638
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