Stable and Metastable States of Human Amylin in Solution

Patients with type II diabetes exhibit fibrillar deposits of human amylin protein in the pancreas. It has been proposed that amylin oligomers arising along the aggregation or fibril-formation pathways are important in the genesis of the disease. In a step toward understanding these aggregation pathw...

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Detalhes bibliográficos
Main Authors: Reddy, Allam S., Wang, Lu, Singh, Sadanand, Ling, Yun L., Buchanan, Lauren, Zanni, Martin T., Skinner, James L., de Pablo, Juan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042569/
https://ncbi.nlm.nih.gov/pubmed/20923655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.014
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