Role of the Conformational Versatility of the Neurotrophin N-Terminal Regions in Their Recognition by Trk Receptors

Neurotrophins (NTs) represent a family of proteins that play an important role in the survival, development, and function of neurons. Extensive efforts are currently being made to develop small molecules endowed with agonist or antagonist NT activity. The structurally versatile N-termini of these pr...

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Detalhes bibliográficos
Main Authors: Stanzione, Francesca, Esposito, Luciana, Paladino, Antonella, Pedone, Carlo, Morelli, Giancarlo, Vitagliano, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042551/
https://ncbi.nlm.nih.gov/pubmed/20923662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.054
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