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ZFNGenome: A comprehensive resource for locating zinc finger nuclease target sites in model organisms

BACKGROUND: Zinc Finger Nucleases (ZFNs) have tremendous potential as tools to facilitate genomic modifications, such as precise gene knockouts or gene replacements by homologous recombination. ZFNs can be used to advance both basic research and clinical applications, including gene therapy. Recentl...

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Détails bibliographiques
Auteurs principaux: Reyon, Deepak, Kirkpatrick, Jessica R, Sander, Jeffry D, Zhang, Feng, Voytas, Daniel F, Joung, J Keith, Dobbs, Drena, Coffman, Clark R
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042413/
https://ncbi.nlm.nih.gov/pubmed/21276248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-83
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