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Segmental duplication as one of the driving forces underlying the diversity of the human immunoglobulin heavy chain variable gene region

BACKGROUND: Segmental duplication and deletion were implicated for a region containing the human immunoglobulin heavy chain variable (IGHV) gene segments, 1.9III/hv3005 (possible allelic variants of IGHV3-30) and hv3019b9 (a possible allelic variant of IGHV3-33). However, very little is known about...

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Detalhes bibliográficos
Main Authors: Pramanik, Sreemanta, Cui, Xiangfeng, Wang, Hui-Yun, Chimge, Nyam-Osor, Hu, Guohong, Shen, Li, Gao, Richeng, Li, Honghua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042411/
https://ncbi.nlm.nih.gov/pubmed/21272357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-78
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