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Effects of prazosin, clonidine, and propranolol on the elevations in brain reward thresholds and somatic signs associated with nicotine withdrawal in rats

RATIONALE: Tobacco withdrawal is characterized by a negative mood state and relatively mild somatic symptoms. Increased noradrenergic transmission has been reported to play an important role in opioid withdrawal, but little is known about the role of noradrenergic transmission in nicotine withdrawal...

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Bibliografische gegevens
Hoofdauteurs: Bruijnzeel, Adrie W., Bishnoi, Mahendra, van Tuijl, Irma A., Keijzers, Kim F. M., Yavarovich, Kate R., Pasek, Tim M., Ford, Jenna, Alexander, Jon C., Yamada, Hidetaka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042243/
https://ncbi.nlm.nih.gov/pubmed/20697697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1970-0
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