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Tbx6-dependent Sox2 regulation determines neural vs mesodermal fate in axial stem cells

The classical view of neural plate development held that it arises from the ectoderm, after its separation from the mesodermal and endodermal lineages. However, recent cell lineage tracing experiments indicate that the caudal neural plate and paraxial mesoderm are generated from common bipotential a...

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Detalhes bibliográficos
Main Authors: Takemoto, Tatsuya, Uchikawa, Masanori, Yoshida, Megumi, Bell, Donald M., Lovell-Badge, Robin, Papaioannou, Virginia E., Kondoh, Hisato
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042233/
https://ncbi.nlm.nih.gov/pubmed/21331042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09729
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