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The use of ultra-dense array CGH analysis for the discovery of micro-copy number alterations and gene fusions in the cancer genome

BACKGROUND: Molecular alterations critical to development of cancer include mutations, copy number alterations (amplifications and deletions) as well as genomic rearrangements resulting in gene fusions. Massively parallel next generation sequencing, which enables the discovery of such changes, uses...

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Detalhes bibliográficos
Main Authors: Przybytkowski, Ewa, Ferrario, Cristiano, Basik, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041991/
https://ncbi.nlm.nih.gov/pubmed/21272361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-4-16
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