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Membrane surface charge dictates the structure and function of the epithelial Na(+)/H(+) exchanger

The Na(+)/H(+) exchanger NHE3 plays a central role in intravascular volume and acid–base homeostasis. Ion exchange activity is conferred by its transmembrane domain, while regulation of the rate of transport by a variety of stimuli is dependent on its cytosolic C-terminal region. Liposome- and cell-...

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Bibliografiska uppgifter
Huvudupphovsmän: Alexander, Robert Todd, Jaumouillé, Valentin, Yeung, Tony, Furuya, Wendy, Peltekova, Iskra, Boucher, Annie, Zasloff, Michael, Orlowski, John, Grinstein, Sergio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041952/
https://ncbi.nlm.nih.gov/pubmed/21245831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.356
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