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Membrane surface charge dictates the structure and function of the epithelial Na(+)/H(+) exchanger
The Na(+)/H(+) exchanger NHE3 plays a central role in intravascular volume and acid–base homeostasis. Ion exchange activity is conferred by its transmembrane domain, while regulation of the rate of transport by a variety of stimuli is dependent on its cytosolic C-terminal region. Liposome- and cell-...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041952/ https://ncbi.nlm.nih.gov/pubmed/21245831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.356 |
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