The Prevalence of Cationic Trypsinogen (PRSS1) and Serine Protease Inhibitor, Kazal Type 1 (SPINK1) Gene Mutations in Polish Patients with Alcoholic and Idiopathic Chronic Pancreatitis

BACKGROUND: The main cause of chronic pancreatitis (CP) is excessive alcohol consumption. On the other hand, only 5–10% of heavy drinkers develop chronic pancreatitis. We have only limited information regarding the pathogenic mechanism by which alcohol leads to the disease. Mutations of the PRSS1 an...

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Main Authors: Gasiorowska, Anita, Talar-Wojnarowska, Renata, Czupryniak, Leszek, Smolarz, Beata, Romanowicz-Makowska, Hanna, Kulig, Andrzej, Malecka-Panas, Ewa
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2010
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041903/
https://ncbi.nlm.nih.gov/pubmed/20676769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-010-1349-4
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