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Activation of the basolateral membrane Cl(−) conductance essential for electrogenic K(+) secretion suppresses electrogenic Cl(−) secretion
Adrenaline activates transient Cl(−)-secretion and sustained K(+)-secretion across isolated distal colonic mucosa of guinea pig. The Ca(++)-activated Cl(−) channel inhibitor CaCCinh-A01 [30μM] significantly reduced electrogenic K(+)-secretion, detected as short-circuit current (I(sc)). This inhibiti...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041851/ https://ncbi.nlm.nih.gov/pubmed/21169331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2010.055038 |
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