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β-Adrenergic activation of electrogenic K(+) and Cl(−) secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways
Adrenergic stimulation of isolated guinea pig distal colonic mucosa produced transient Cl(−) and sustained K(+) secretion. Transient short-circuit current (I(sc)) depended on β(2)-adrenergic receptors (β(2)-AdrR), and sustained I(sc) relies on a β(1)-AdrR/β(2)-AdrR complex. Epinephrine (epi) increas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904107/ https://ncbi.nlm.nih.gov/pubmed/20413718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00035.2010 |
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