Survival Benefit With Proapoptotic Molecular and Pathologic Responses From Dual Targeting of Mammalian Target of Rapamycin and Epidermal Growth Factor Receptor in a Preclinical Model of Pancreatic Neuroendocrine Carcinogenesis

PURPOSE: Pancreatic neuroendocrine tumors (PNETs), although rare, often metastasize, such that surgery, the only potentially curative therapy, is not possible. There is no effective systemic therapy for patients with advanced PNETs. Therefore, new strategies are needed. Toward that end, we investiga...

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Hlavní autoři: Chiu, Christopher W., Nozawa, Hiroaki, Hanahan, Douglas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2010
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041788/
https://ncbi.nlm.nih.gov/pubmed/20823411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.28.0198
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