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SFRP1 reduction results in an increased sensitivity to TGF-β signaling
BACKGROUND: Transforming growth factor (TGF)-β plays a dual role during mammary gland development and tumorigenesis and has been shown to stimulate epithelial-mesenchymal transition (EMT) as well as cellular migration. The Wnt/β-catenin pathway is also implicated in EMT and inappropriate activation...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041779/ https://ncbi.nlm.nih.gov/pubmed/21303533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-59 |
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