Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors

Recombinant Towne CMV expressing luciferase under the control of CMV-DNA polymerase (POL) or the late pp28 (UL99) promoters were evaluated for potential application in high-throughput screening of anti-viral compounds. POL-and pp28-luciferase displayed maximal expression 48 and 72 hours post infecti...

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Main Authors: He, Ran, Sandford, Gordon, Hayward, Gary S, Burns, William H, Posner, Gary H, Forman, Michael, Arav-Boger, Ravit
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041771/
https://ncbi.nlm.nih.gov/pubmed/21269468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-40
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