Reduced Stability and Increased Dynamics in the Human Proliferating Cell Nuclear Antigen (PCNA) Relative to the Yeast Homolog

Proliferating Cell Nuclear Antigen (PCNA) is an essential factor for DNA replication and repair. PCNA forms a toroidal, ring shaped structure of 90 kDa by the symmetric association of three identical monomers. The ring encircles the DNA and acts as a platform where polymerases and other proteins doc...

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Detalhes bibliográficos
Main Authors: De Biasio, Alfredo, Sánchez, Ricardo, Prieto, Jesús, Villate, Maider, Campos-Olivas, Ramón, Blanco, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041752/
https://ncbi.nlm.nih.gov/pubmed/21364740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016600
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