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Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells

Cancer progression is an abnormal form of tissue repair characterized by chronic inflammation. IκB kinase-β (IKKβ) required for nuclear factor-κB (NF-κB) activation plays a critical role in this process. Using EOC cells isolated from malignant ovarian cancer ascites and solid tumors, we identified I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, R, Alvero, AB, Silasi, DA, Kelly, MG, Fest, S, Visintin, I, Leiser, A, Schwartz, PE, Rutherford, T, Mor, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041589/
https://ncbi.nlm.nih.gov/pubmed/18408758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.112
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