Altered Proliferation and Differentiation Properties of Primary Mammary Epithelial Cells from BRCA1 Mutation Carriers

Female BRCA1 mutation carriers have a nearly 80% probability of developing breast cancer during their life-time. We hypothesized that the breast epithelium at risk in BRCA1 mutation carriers harbors mammary epithelial cells (MEC) with altered proliferation and differentiation properties. Using a thr...

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Autori principali: Burga, Laura N., Tung, Nadine M., Troyan, Susan L., Bostina, Mihnea, Konstantinopoulos, Panagiotis A., Fountzilas, Helena, Spentzos, Dimitrios, Miron, Alexander, Yassin, Yosuf A., Lee, Bernard T., Wulf, Gerburg M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041511/
https://ncbi.nlm.nih.gov/pubmed/19190334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2954
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