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Measurement of 8-hydroxy-2′-deoxyguanosine in DNA by high-performance liquid chromatography-mass spectrometry: comparison with measurement by gas chromatography-mass spectrometry

Measurement of 8-hydroxy-2′-deoxyguanosine (8-OH-dGuo) in DNA by high-performance liquid chromatography/mass spectrometry (LC/MS) was studied. A methodology was developed for separation by LC of 8-OH-dGuo from intact and modified nucleosides in DNA hydrolyzed by a combination of four enzymes: DNase...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Dizdaroglu, Miral, Jaruga, Pawel, Rodriguez, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.e12
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