Measurement of 8-hydroxy-2′-deoxyguanosine in DNA by high-performance liquid chromatography-mass spectrometry: comparison with measurement by gas chromatography-mass spectrometry

Measurement of 8-hydroxy-2′-deoxyguanosine (8-OH-dGuo) in DNA by high-performance liquid chromatography/mass spectrometry (LC/MS) was studied. A methodology was developed for separation by LC of 8-OH-dGuo from intact and modified nucleosides in DNA hydrolyzed by a combination of four enzymes: DNase...

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Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Dizdaroglu, Miral, Jaruga, Pawel, Rodriguez, Henry
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 2001
Pynciau:	NAR Methods Online
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30413/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.e12
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