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Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action

BACKGROUND AND PURPOSE: Two non-psychoactive cannabinoids, cannabidiol (CBD) and cannabichromene (CBC), are known to modulate in vitro the activity of proteins involved in nociceptive mechanisms, including transient receptor potential (TRP) channels of vanilloid type-1 (TRPV1) and of ankyrin type-1...

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Détails bibliographiques
Auteurs principaux: Maione, Sabatino, Piscitelli, Fabiana, Gatta, Luisa, Vita, Daniela, De Petrocellis, Luciano, Palazzo, Enza, de Novellis, Vito, Di Marzo, Vincenzo
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041249/
https://ncbi.nlm.nih.gov/pubmed/20942863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01063.x
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