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HdmX overexpression inhibits oncogene induced cellular senescence
Cellular senescence is an irreversible state of terminal growth arrest that requires functional p53. Acting to block tumor formation, induction of senescence has also been demonstrated to contribute to tumor clearance via the immune system following p53 reactivation.1,2 the Hdm2-antagonist, Nutlin-3...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041169/ https://ncbi.nlm.nih.gov/pubmed/20724842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.16.12779 |
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