Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation

Ryanodine receptors (RyR) amplify activity-dependent calcium influx via calcium-induced calcium release. Calcium signals trigger postsynaptic pathways in hippocampal neurons that underlie synaptic plasticity, learning, and memory. Recent evidence supports a role of the RyR2 and RyR3 isoforms in thes...

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Bibliographic Details
Main Authors: Adasme, Tatiana, Haeger, Paola, Paula-Lima, Andrea C., Espinoza, Italo, Casas-Alarcón, M. Mercedes, Carrasco, M. Angélica, Hidalgo, Cecilia
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041089/
https://ncbi.nlm.nih.gov/pubmed/21282625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013580108
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