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Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

Insulin receptors (IRs) are expressed in discrete neuronal populations in the central nervous system, including the hippocampus. To elucidate the functional role of hippocampal IRs independent of metabolic function, we generated a model of hippocampal-specific insulin resistance using a lentiviral v...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Diabetes
Päätekijät: Grillo, Claudia A., Piroli, Gerardo G., Lawrence, Robert C., Wrighten, Shayna A., Green, Adrienne J., Wilson, Steven P., Sakai, Randall R., Kelly, Sandra J., Wilson, Marlene A., Mott, David D., Reagan, Lawrence P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Diabetes Association 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613975/
https://ncbi.nlm.nih.gov/pubmed/26216852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0596
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