Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

Insulin receptors (IRs) are expressed in discrete neuronal populations in the central nervous system, including the hippocampus. To elucidate the functional role of hippocampal IRs independent of metabolic function, we generated a model of hippocampal-specific insulin resistance using a lentiviral v...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Grillo, Claudia A., Piroli, Gerardo G., Lawrence, Robert C., Wrighten, Shayna A., Green, Adrienne J., Wilson, Steven P., Sakai, Randall R., Kelly, Sandra J., Wilson, Marlene A., Mott, David D., Reagan, Lawrence P.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2015
Fag:
Complications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613975/
https://ncbi.nlm.nih.gov/pubmed/26216852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0596
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